Table 1.
Expression-invariant genes in E. coli during DNA damage as identified by the DP scheme and used for moose 2
| Gene | Product | Process/Function |
|---|---|---|
| cysG a | uroporphyrin III C-methyltransferase | Other |
| dnaG | DNA primase | DNA replication |
| dtpB | dipeptide/tripeptide:H+ symporter DtpB | Transport |
| ftsX | Cell division protein ftsX | Cell division |
| ftsY | Cell division protein ftsY | Cell division |
| glyY | tRNAglyY | Translation |
| gyrB | DNA gyrase, subunit B | DNA replication |
| hcaT a | putative transport protein, major facilitator superfamily (MFS) | Transport |
| idnT a | L-idonate / 5-ketogluconate / gluconate transporter IdnT | Transport |
| ihfB a | integration host factor (IHF), beta subunit | Transcription |
| lhr | member of ATP-dependent helicase superfamily II | DNA replication |
| mutM | formamidopyrimidine DNA glycosylase | DNA repair |
| mutY | A/G-specific adenine glycosylase | DNA repair |
| ndk | nucleoside diphosphate kinase | Other |
| nfuA | iron-sulfur cluster scaffold protein | Other |
| pnp | polynucleotide phosphorylase monomer | RNA processing |
| rbbA | ribosome-associated ATPase | Translation |
| rhsB | RhsB protein in rhs element | Other |
| rpsU | 30S ribosomal subunit protein S21 | Translation |
| rrsA a | 16S ribosomal RNA (rrsA) | Translation |
| rrsE | 16S ribosomal RNA (rrsE) | Translation |
| rrsG | 16S ribosomal RNA (rrsG) | Translation |
| secB | SecB chaperone | Protein localization |
| spoT | Guanosine-3′,5′-bis(diphosphate) 3′-pyrophosphohydrolase | Other |
| ssrA a | tmRNA | Trans-translation |
| tfaR | Rac prophage; predicted tail fiber assembly protein | Prophage |
| thrW | tRNAthrW | Translation |
| valS | Valyl-tRNA synthetase | Translation |
| yedJ | predicted phosphohydrolase | Other |
| ynaE | Rac prophage; cold shock protein, function unknown | Prophage |
| yphG | conserved protein | Unknown |
| zntA | zinc, cadmium and lead efflux system | Transport |
| zupT | heavy metal divalent cation transporter ZupT | Transport |
aEstablished reference genes in E. coli (see main text and Fig. 2b) were used as an input for moose 2