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(A) Glucose-stimulated insulin secretion assay of free islets and islets embedded in modules with and without HUVEC. There were no significant differences (P = 0.076) in the insulin stimulation index among the three groups after 4 d of culture in vitro. (B) Absolute values of insulin secreted at basal and stimulated glucose solutions. n = 3 in each group; error bars in A indicate SEM.
