Eiger expression in development and in JNK-driven epithelial tumors. (A–H) Larval wing primordia from WT individuals (A–C) or from individuals expressing the indicated transgenes under the control of the ap-GAL4 driver (D–H) and stained for DAPI (blue, A–H), Cut (red in A–C), eiger-lacZ (green, A, B, D, and F), Eiger-GFP (green, C, E, G, and H), He (red, E, G, and H), and MyrT (red, D and F). Eiger is expressed in myoblasts (labeled by the expression of Cut) in WT wing discs (A–C) and becomes activated in a scattered pattern in epithelial cells (labeled by the expression of MyrT) and recruited hemocytes (labeled by the expression He) in JNK-driven tumor-like overgrowths (D–H). (Scale bars, A, C, D, F, and H, 50 µm; E and G, 15 µm.)