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. 2017 Sep 4;36:117. doi: 10.1186/s13046-017-0576-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Up-regulation of CCN2 and LRP6 correlates with poor prognosis and in HCC patients. a, b, c Kaplan-Meier’s curves for OS and TTR according to CCN2 and LRP6 expression in the validation cohort (n = 374). High expression levels of CCN2 and/or LRP6 are associated with poor prognosis of HCCs. d CCN2 and LRP6 expression in tumor with early recurrence (<24 months) and those without (n = 8)