Figure 2.

Trends in study outcomes over the course of the randomized trial. Plots of observed trends in outcomes for each study participant (gray lines) and of estimated trends in means (heavy black lines). The 95% confidence intervals are shown for the time-specific estimates (vertical lines). Solid lines represent results observed during treatment with amiloride, and dashed lines represent results observed during treatment for hydorchlorothiazide. (a) SBP results, (b) serum potassium (K⁺) results, and (c) weight results.