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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2017 Jul 26;57:133–138. doi: 10.1016/j.dnarep.2017.07.008

Fig. 1. Double knockout Ku70−/−XLF−/− mice are viable.

Fig. 1

The number of thirty-day-old mice (P30) of indicated genotypes. Top. Combined inactivation of XLF and DNA-PKcs leads to perinatal lethality. No DNA-PKcs−/−XLF−/− mice survived longer than day P5 (*). Middle. Mice with combined inactivation of Ku70 and XLF are live-born and develop as Ku70-deficient littermates. Bottom. Mice with combined inactivation of Ku70 and DNA-PKcs are live-born and develop as Ku70-deficient littermates.