Skip to main content
. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: J Immunol. 2017 Aug 2;199(5):1748–1761. doi: 10.4049/jimmunol.1700472

Figure 1. Blood glucose levels increase upon infection with HSV-1.

Figure 1

C57BL/6 animals were either infected with 1 × 104 PFU of HSV-RE or left alone. (A,B) Blood glucose levels were measured at time points indicated post infection. (A) Line graph showing kinetics of blood glucose levels (fed state) in control, day 4, day 8 and day 15 pi. (B) Histogram showing fed state and fasting state blood glucose levels at day 15 pi. (C) Line graph showing changes in serum cytokine levels at different time points pi. (D) Line graph showing changes in gene expression in the liver at different time points pi. (E) Histogram representing the expression of CYP7A1 and RHOC in liver of naïve and day 8 pi animals. Data represents the mean ± SEM of more than 8 independent experiments for A, B (n = 5–8 mice/group) and 2 independent experiments for C-E (n=4–5 mice/group). Data were analyzed with One-way ANOVA for A, C & D compared to the control or student’s t-test for B & E. P≤ 0.0001 (****), P≤0.001(***), P≤0.01(**), P≤0.05(*).