Table 2.
Ordinal Logistic Regression Analysis for Quintiles of Final Intracerebral Hemorrhage (ICH) Volumea
| Variable | Lobar ICH (n = 254) | Deep ICH (n = 164) | ||
|---|---|---|---|---|
|
|
|
|||
| Adjusted OR (95% CI) | P Value | Adjusted OR (95% CI) | P Value | |
| Age | 0.97 (0.95–0.99) | .01 | 0.94 (0.91–0.97) | <.001 |
|
| ||||
| Female | 1.18 (0.93–1.51) | .18 | 0.63 (0.45–0.87) | .005 |
|
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| Acute-Phase CT Features | ||||
|
| ||||
| Time to final CT ≤6 vs >6 hb | 1.60 (1.16–2.23) | .005 | 0.90 (0.58–1.4) | .64 |
|
| ||||
| Presence of spot sign | 2.98 (1.58–5.82) | .001 | 4.14 (1.98–8.99) | <.001 |
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| Baseline IVH | 1.76 (1.34–2.33) | <.001 | 1.97 (1.41–2.79) | <.001 |
|
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| MRI SVD Markers | ||||
|
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| WMH volumec | 1.07 (0.84–1.36) | .58 | 1.49 (0.98–1.79) | .09 |
|
| ||||
| Absence of CMBs | 1.41 (1.11–1.81) | .006 | 1.43 (1.04–1.99) | .03 |
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| ||||
| Presence of cortical superficial siderosis | 1.49 (1.14–1.94) | .004 | NA | NA |
Abbreviations: CMBs, cerebral microbleeds; CT, computed tomographic; IVH, intraventricular hemorrhage; MRI, magnetic resonance imaging; NA, not applicable; OR, odds ratio; SVD, small vessel disease; WMH, white matter hyperintensity.
a
The adjusted OR is for final ICH volume (defined as the largest volume within 48 hours after symptom onset) quintile increase. For continuous dependent variables, the OR is over the entire range.
b
See the Methods section, Computed Tomography subsection, for definition of this term.
c
Variable was log-transformed in the multivariable model.