. Author manuscript; available in PMC: 2017 Sep 5.

Published in final edited form as: JAMA Neurol. 2016 Aug 1;73(8):961–968. doi: 10.1001/jamaneurol.2016.1218

Table 3.

Multivariable Analysis of Hematoma Expansion^a

Variable	Development Cohort (n = 784)		Replication Cohort (n = 245)
Variable	AOR (95% CI)	P Value	AOR (95% CI)	P Value
Hypodensities	3.42 (2.21–5.31)	<.001	4.37 (2.05–9.62)	<.001

Presence vs absence of spot sign	2.72 (1.56–4.75)	<.001	3.34 (1.62–7.00)	<.001

Warfarin use	1.99 (1.27–3.11)	<.001	3.43 (1.47–8.20)	<.001

<6 vs ≥6 h From symptom onset to baseline CT	1.82 (1.11–3.07)	.03	4.64 (1.23–24.02)	.01

Baseline ICH volume^b	1.17 (0.27–4.69)	.83	0.97 (0.14–6.58)	.98

Baseline IVH volume^b	2.12 (0.36–11.6)	.40	1.84 (0.20–13.19)	.57

Abbreviations: AOR, adjusted odds ratio; CT, computed tomography; ICH, intracerebral hemorrhage; IVH, intraventricular hemorrhage.

Model is adjusted for age and sex.

Per change in regressor over entire range.