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A. Tazemetostat induced changes in H3K27me3:H3 ratios in treated xenografts as measured by ELISA; controls (solid bars), treated (open bars). B. Relative expression levels of EZH2 in xenograft and cell line models. Data are expressed around the mean expression level (0) for the complete datset. The results show lower than mean levels of expression for rhabdoid tumors KT-12, KT-14, NCH-RBD1, NCH-RBD2, BT-29, marked with arrows (Agilent SurePrint G3 arrays).
