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Percent change in the cerebral metabolic rate of oxygen (CMRO2) from baseline to the end the normal apnea (NM), apnea following 5 min of hyperventilation (HV), and apnea following 15 min of 100% O2 hyperventilation (HX). The reduction in CMRO2 was significantly larger in the HX compared to the HV apnea. Error bars denote 95% confidence intervals.
