Figure 1.

Effect of fasudil on changes in collateral perfusion during ischemia. (a) Graph showing changes in collateral perfusion calculated as percent change from prior to treatment (30 min after filament occlusion). Changes in collateral perfusion was minimal and mostly negative in vehicle-treated SHR. Fasudil did not significantly increased collateral perfusion. Graphs showing (b) number, (c) duration, and (d) magnitude of increased collateral perfusion events in vehicle or fasudil-treated SHR. Fasudil treatment did not increase these discrete events.