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Doxycycline significantly inhibits proliferation and induces apoptosis in glioblastoma cancer cells. Doxycycline inhibits proliferation (A) and induces apoptosis (B) of two glioblastoma cell lines A172 and U87 in a dose-dependent manner. (C) Representative Western blot image showing the levels of PCNA and cleaved caspase 3 in A172 and U87 exposed to doxycycline. These data were derived from three independent experiments. * p<0.05 compared to control.
