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. 2017 Jun 26;16(16):1487–1488. doi: 10.1080/15384101.2017.1345237

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© 2017 The Author(s). Published with license by Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 1. — The R₁ aromatic side chain of imipridone derivatives ONC201, ONC206, and ONC212 provides new directions for nanomolar anti-cancer potency via TRAIL with unique characteristics.