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. 2017 Aug 26;12:6239–6257. doi: 10.2147/IJN.S143293

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© 2017 Li et al. This work is published and licensed by Dove Medical Press Limited

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Antitumor effects of MSNs-DM1@PDA-PEG-APt in nude mice bearing SW480 tumors. (A) Tumor growth curves in nude mice bearing SW480 tumors after treatment. (B) Tumor images at sacrifice. (C) Tumor weights at study end. (D) H&E staining of tumor sections collected from the sacrificed mice.

Notes: Data are expressed as mean ± SD (n=4, *P<0.05, **P<0.01). Scale bar: 100 µm. Arrows refer to tissue necrosis.

Abbreviations: MSNs, mesoporous silica nanoparticles; PDA, hydrochloride dopamine; PEG, polyethylene glycol; APt, aptamer; SD, standard deviation; H&E, hematoxylin and eosin.