Table 2.

Performance comparison of SuccinSite2.0 with existing predictors using independent testing dataset

Measurements/predictors	Sp	Sn	Ac	MCC
iSuc-PseAAC	0.887	0.122	0.827	0.013
iSuc-PseOpt	0.758	0.303	0.722	0.038
pSuc-Lys	0.826	0.224	0.779	0.036
SuccinSite	0.882	0.371	0.842	0.199
SuccinSite2.0	0.884	0.457	0.850	0.263

Notes: The threshold values of iSuc-PseAAC, iSuc-PseOpt, pSuc-Lys, and SuccinSite were the same as defined in the servers. The SuccinSite2.0 threshold was controlled at 90% specificity based on training set performances.

Abbreviations: Ac, including accuracy; MCC, Matthews correlation coefficient; Sn, sensitivity; Sp, specificity.