Table 3.

Performance comparison of SuccinSite2.0 with existing predictors using the new dataset

Measurements/predictors	Sp	Sn	Ac	MCC
iSuc-PseAAC	0.814	0.188	0.766	0.001
iSuc-PseOpt	0.797	0.234	0.754	0.020
pSuc-Lys	0.808	0.243	0.767	0.032
SuccinSite	0.858	0.290	0.815	0.109
SuccinSite2.0	0.857	0.338	0.816	0.145

Notes: The threshold values of iSuc-PseAAC, iSuc-PseOpt, pSuc-Lys, and SuccinSite were the same as defined in the servers. And the proposed SuccinSite2.0 threshold was controlled at ~90% specificity based on training set performances.

Abbreviations: Ac, including accuracy; MCC, Matthews correlation coefficient; Sn, sensitivity; Sp, specificity.