Table 2. Univariate associations between leukocytosis and outcomes.
Variable | WBC<11k | WBC> = 11k | n | p-value | |||
---|---|---|---|---|---|---|---|
n | n | ||||||
10116 | 863 | 10979 | |||||
Operative Time | 263.150 | 103.621 | 259.424 | 111.314 | 10976 | 0.343 | |
Blood Transfusions | 3311/10116 | 32.7% | 303/863 | 35.1% | 10979 | 0.164 | |
Total Hospital Stay (days) | 9.878 | 9.786 | 11.648 | 8.722 | 10960 | <0.001 | |
30-Day Mortality | 253/10116 | 2.5% | 33/863 | 3.8% | 10979 | 0.026 | * |
Wound Complications (composite) | 405/10116 | 4.0% | 47/863 | 5.4% | 10979 | 0.050 | |
Superficial Incisional SSI | 311/10116 | 3.1% | 31/863 | 3.6% | 10979 | 0.460 | |
Deep Incisional SSI | 44/10116 | 0.4% | 5/863 | 0.6% | 10979 | 0.730 | |
Organ/Space SSI | 29/10116 | 0.3% | 6/863 | 0.7% | 10979 | 0.084 | |
Wound Disruption | 42/10116 | 0.4% | 11/863 | 1.3% | 10979 | 0.001 | * |
Medical Complications (composite) | 1513/10116 | 15.0% | 197/863 | 22.8% | 10979 | <0.001 | * |
Unplanned Reintubation | 343/10116 | 3.4% | 39/863 | 4.5% | 10979 | 0.101 | |
Pulmonary Embolism | 60/10116 | 0.6% | 10/863 | 1.2% | 10979 | 0.075 | |
On Ventilator > 48 Hours | 604/10116 | 6.0% | 102/863 | 11.8% | 10979 | <0.001 | * |
Progressive Renal Insufficiency | 90/10116 | 0.9% | 11/863 | 1.3% | 10979 | 0.341 | |
Acute Renal Failure | 178/10116 | 1.8% | 26/863 | 3.0% | 10979 | 0.013 | * |
Urinary Tract Infection | 197/10116 | 1.9% | 19/863 | 2.2% | 10979 | 0.698 | |
Stroke/CVA | 171/10116 | 1.7% | 24/863 | 2.8% | 10979 | 0.028 | * |
Coma Greater Than 24 Hours | 22/10116 | 0.2% | 4/863 | 0.5% | 10979 | 0.288 | |
Cardiac Arrest Requiring CPR | 209/10116 | 2.1% | 15/863 | 1.7% | 10979 | 0.597 | |
Myocardial Infarction | 54/10116 | 0.5% | 6/863 | 0.7% | 10979 | 0.706 | |
Pneumonia | 365/10116 | 3.6% | 54/863 | 6.3% | 10979 | <0.001 | * |
Deep Venous Thrombosis | 149/10116 | 1.5% | 25/863 | 2.9% | 10979 | 0.002 | * |
Sepsis | 170/10116 | 1.7% | 26/863 | 3.0% | 10979 | 0.007 | * |
Septic Shock | 125/10116 | 1.2% | 13/863 | 1.5% | 10979 | 0.599 |
Univariate associations between leukocytosis (>11,000 white blood cell count per microliter) and outcomes. Continuous variables are expressed as a mean and standard deviation, while categorical variables are expressed as a proportion and percentage. SSI = Surgical Site Infection; CVA = Cerebrovascular Accident; CPR: Cardiopulmonary Resuscitation
* indicates statistically significant p-values at the 0.05 significance level.