Table 1. Clinical trial interventions and associated costs and effects considered in HIV transmission simulation model.

Uniform distributions were used for all costs and lognormal distribution for all effects in probabilistic analyses. Intervention costs were derived from India-specific sources.[35,49–51] Cost in 2012 USD.

Intervention	Risk pathway	Effect RR (95% CI)	Session Length (Hours)	Cost (Range)	RR Ref.
Alcohol: Brief individual counseling	Alcohol use	0.68 (0.50–0.93)	1	$1.64 (0.5x-1.5x)	[27]
Alcohol: Long individual counseling	Alcohol use	0.36 (0.15–0.82)	4	$6.56 (0.5x-1.5x)	[27]
Alcohol: Brief group counseling	Alcohol use	0.62 (0.42–0.91)	5	$1.64 (0.5x-1.5x)	[27]
Alcohol: Long group counseling	Alcohol use	0.47 (0.25–0.86)	18	$5.90 (0.5x-1.5x)	[27]
Sex risk: Brief individual counseling	Condom use	0.97 (0.95–0.99)	1	$1.64 (0.5x-1.5x)	[25]
	STI prevalence	0.84 (0.73–0.96)
Sex risk: Long individual counseling	Condom use	0.92 (0.85–0.98)	9	$14.76 (0.5x-1.5x)	[25]
	STI prevalence	0.64 (0.44–0.89)
Sex risk: Brief group counseling	Condom use	0.97 (0.94–0.99)	5	$1.64 (0.5x-1.5x)	[25]
	STI prevalence	0.81 (0.68–0.95)
Sex risk: Long group counseling	Condom use	0.94 (0.90–0.99)	18	$5.90 (0.5x-1.5x)	[25]
	STI prevalence	0.71 (0.54–0.92)
Sex risk: Community intervention	Condom use	0.97 (0.94–0.99)	ongoing	$6.66 (0.5x-1.5x)	[26]
	STI prevalence	0.78 (0.59–1.0)
Depression: Brief individual counseling	Depression	0.84 (0.43–1.0)	8	$13.12 (0.5x-1.5x)	[28]
Depression: Long individual counseling	Depression	0.62 (0.28–1.0)	22	$36.08 (0.5x-1.5x)	[28]
Depression: Brief group counseling	Depression	0.81 (0.65–0.97)	11	$3.61 (0.5x-1.5x)	[28]
Depression: Long group counseling	Depression	0.71 (0.58–0.84)	22	$7.22 (0.5x-1.5x)	[28]
Adherence: Brief counseling	ART Adherence	0.67 (0.53–0.84)	1	$6.56 (0.5x-1.5x)	[24]
Adherence: Weekly SMS	ART Adherence	0.75 (0.58–0.96)	4	$2.46 (0.5x-1.5x)	[24]