Table 2.

Preclinical Studies on the effects of waterpipe smoking

Health Outcomes of WP	Publication	Study Type	Species
Pregnancy complications (low birth-weight and neonatal death)	Khabour et al 201675	In vivo	Rats
Cardiovascular disease	Rammah et al 201367	In vitro	Human aortic endothelial cells
Adverse/impaired memory effects	Alzoubi et al 201564	In vivo	Rats
Reduced cell proliferation	Shihadeh et al 201469	In vitro	Human alveolar cells
Inflammation in lung	Khabour et al 2015 b65	In vivo	Mice
	Khabour et al 201266	In vivo	Mice