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. 2017 Sep 5;7:10547. doi: 10.1038/s41598-017-10593-7

Table 2.

Motor symptoms and non-motor symptoms of PD-RLS and PD-NRLS groups.

PD-RLS group (88 cases) PD-NRLS group (130 cases) P value
Motor symptoms
  H-Y stage [stage, median (quartile)] 2.00 (1.50, 2.50) 1.50 (1.00, 2.50) 0.00**
  UPDRS III [points, median (quartile)] 26.75 (19.00, 41.75) 20.00 (11.50, 29.00) 0.00**
  Levodopa equivalent daily dose [mg, median (quartile)] 1.88 (0.00, 3.75) 0.00 (0.00, 2.50) 0.01*
Non-motor symptoms
  HAMD [points, median (quartile)] 15.00 (9.00, 20.00) 8.00 (3.00, 14.75) 0.00**
  HAMA [points, median (quartile)] 11.00 (6.00, 19.00) 6.00 (2.00, 11.00) 0.00**
  PSQI [points, median (quartile)] 7.00 (5.00, 10.00) 5.00 (3.00, 9.00) 0.00**
  MAES (points, mean ± SD) 18.62 ± 8.32 14.70 ± 9.00 0.01*
  FSS (points, mean ± SD) 41.27 ± 20.03 20.78 ± 35.45 0.04*
  SCOPA-AUTO score [points, median (quartile)] 11.00 (7.00, 18.00) 9.00 (5.00, 28.25) 0.06
  MoCA [points, median (quartile)] 20.00 (15.00, 24.75) 21.50 (16.00, 25.00) 0.23

Two-tailed t test was used for the comparison of scores of MAES and FSS between PD-RLS and PD-NRLS groups; Nonparametric test was used for the comparison of motor symptoms and for the comparison of scores of HAMD, HAMA, PSQI, SCOPA-AUTO score and MoCA. H-Y stage = Hohen and Yahr stage; UPDRS = Unified Parkinson Disease Rating Scale; HAMD = Hamilton Depression Scale; HAMA = Hamilton Anxiety Scale; PSQI = Pittsburgh Sleep Quality Index; MAES = Modified Indifference Rating Scale; FSS = Fatigue Severity Scale; MoCA = Montreal Cognitive Assessment; SCOPA-AUTO = Scale for Outcomes in Parkinson Disease for Autonomic Symptoms. *P < 0.05, **P < 0.01.