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. 2017 Sep 5;7:10550. doi: 10.1038/s41598-017-10338-6

Figure 1.

Figure 1

Mycophenolic acid blocks T cell proliferation and promotes apoptosis. (A) Cell viability after incubation with 0.5 µM MPA or vehicle for 24 h and 48 h. The data are from four independent experiments. Mann-Whitney U test: *P < 0.05. (B) Cell proliferation of CFSE-stained Jurkat cells. The cells were incubated with 0.5 µM MPA or vehicle for up to 96 h. (C) Cell cycle analysis of PI-stained Jurkat cells. The cells were incubated for up to 72 h with 0.5 MPA or vehicle. The data are from three independent experiments. (D) (Left) Images representing live cells (green) and apoptotic cells (red) after 24 h and 48 h of incubation with 0.5 µM MPA. (Right) Histograms representing the percentage of apoptotic cells after 24 h and 48 h exposure to vehicle or MPA. The data are from three independent experiments.