Table 4.

Multivariable-adjusted associations between distinct biochemical parameters and PAPP-A2 concentration (in pg/mL) in all women and stratified by women with and without menstrual cycles^a.

	All women (n = 230)		Women with menstrual cycles  (n = 113)		Women without menstrual cycles (n = 112)		p for difference
	Diff. in PAPP-A2 conc. (pg/mL)	p-value	Diff. in PAPP-A2 conc. (pg/mL)	p-value	Diff. in PAPP-A2 conc. (pg/mL)	p-value
Per SD difference in
Haemoglobin	−33.6	0.002	−17.7	0.16	−46.1	0.007	0.27
Haematocrit	−30.5	0.002	−15.9	0.18	−38.8	0.009	0.42
Red blood cells	−36.4	0.0002	−11.0	0.41	−46.7	0.0007	0.19

PAPP-A2, pregnancy-associated plasma protein-A2; diff., difference; conc., concentration.

^aSeparate linear regression models for each biochemical parameter adjusted for age (continuously), weight (continuously) and pretest.