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. 2017 Sep 5;7:10490. doi: 10.1038/s41598-017-09981-w

Figure 6.

Figure 6

IIRMIs in Betaseron Induces inflammatory response by in vivo and response. (a–c) IFNAR knockout mice (n = 4–6/group) were injected with 1 × 106 IU of Rebif, Betaseron or saline in 50 μL volume SC. After 5 h, mRNA levels of il-6, il-1β and ccl5 were quantified from skin lysates. Data derived from mean ± SD from two independent experiments. Statistical differences as determined by Bartlett’s ANOVA **p < 0.01.