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. 2017 Sep 5;7:10497. doi: 10.1038/s41598-017-10807-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Boxplots of the relative concentrations for the significantly altered metabolites and ratios in serum of patients considering t test, Pearson correlation coefficient and multivariate analyses. Data is shown in the Supplementary Table S1. X axes represent the fibrosis degree (METAVIR Score), Y axes represent relative units of the semiquantified metabolites or ratios. The bar plots show the normalized values. The boxes range from the 25% and the 75% percentiles; the 5% and 95% percentiles are indicated as error bars; single data points are indicated by dots. Medians are indicated by horizontal lines within each box.