Table 4.
Hypertension control: intention to treat analysis
| Blood pressure outcomes | Intervention (N = 110) | Control (N = 115) | Adjusted final means (standard error) | Adjusted mean difference (95% CI) intervention versus control | p value | |
|---|---|---|---|---|---|---|
| Intervention | Control | |||||
| Final mean 24-h SBP (mmHg): (range), median | (102.4, 173.7) 132.0 | (107.9, 174.1) 132.9 | 132.8 (1.2) | 133.9 (1.1) | −1.1 (−4.2, 2.0) | 0.48 |
| Mean ± standard deviation | 132.7 ± 14.1 | 133.8 ± 14.0 | ||||
| Change in mean 24-h SBP (mmHg): (range), median | (−44.4, 29.4) −0.5 | (−42.9, 26.3) −0.1 | ||||
| Mean ± standard deviation | −2.4 ± 12.5 | −1.6 ± 11.3 | ||||
| Final DDD: (range), median | (0.0,10.1) 2.5 | (0.0,11.5) 2.7 | 3.1 (0.1) | 3.1 (0.1) | 0.0 (−0.4, 0.4) | 0.51 |
| Mean ± standard deviation | 3.0 ± 2.5 | 3.2 ± 2.2 | ||||
| Change in DDD: (range), median | (−3.0, 4.8) 0.0 | (−5.0, 5.3) 0.0 | ||||
| Mean ± standard deviation | 0.1 ± 1.2 | 0.0 ± 1.5 | ||||
| Final medication-adjusted SBP (mmHg): (range), median | (112.8, 240.1) 154.1 | (110.0, 248.5) 156.8 | 158.4 (1.7) | 158.7 (1.6) | −0.2 (−4.8, 4.4) | 0.93 |
| Mean ± standard deviation | 157.3 ± 28.2 | 158.8 ± 25.5 | ||||
| Change in medication-adjusted SBP (mmHg): (range), median | (−50.6,39.8) −0.2 | (−42.9, 45.0) 0.5 | ||||
| Mean ± standard deviation | −1.3 ± 16.7 | −1.3 ± 15.8 | ||||
| Final nocturnal blood pressure dipping patterns: n (%) | Odds ratio (95% CI) | |||||
| Extreme: ≥20% fall in SBP at night/sleep | 2 (1.8) | 2 (1.7) | 0.96 (0.55, 1.71) | 0.90 | ||
| Normal: ≥10 but <20% fall in SBP at night/sleep | 16 (14.6) | 17 (14.8) | ||||
| None: <10 to ≤0% fall at night/sleep | 40 (36.4) | 49 (42.6) | ||||
| Reverse: SBP at night/sleep greater than daytime/awake |
22 (20.0) | 23 (20.0) | ||||
Modeling the probability of having greater nighttime dipping