Table 2.
Characteristics of IPMN cases in the cohort (N = 51).
| Variable | Benign1 IPMNs (n = 21) | Malignant2 IPMNs (n = 30) | pvalue |
|---|---|---|---|
| Age at diagnosis, mean (SD)(yrs) | 68.4 (9.8) | 68.6 (10.3) | 0.939 |
| Male: Female, n (%) | 8(38):13(62) | 19(63):11(37) | 0.075 |
| Body mass index (BMI), mean (SD) | 26.5 (4.6) | 27.9 (4.6) | 0.355 |
| Positive personal history of diabetes | 4 (19) | 4 (13) | 0.621 |
| Positive personal history of chronic pancreatitis | 5 (24) | 9 (30) | 0.126 |
| Had abdominal pain as presenting symptom | 7 (37) | 11 (37) | 0.165 |
| Had weight loss as presenting symptom | 3 (14) | 8 (27) | 0.110 |
| Had jaundice as presenting symptom | 1 (5) | 8 (27) | 0.012 |
| Pre-operative serum CA 19-9 levels, mean (SD)(ng/mL) | 91 (314) | 692 (1493) | 0.125 |
| Pre-operative serum albumin levels, mean (SD)(ng/mL) | 4.4 (0.98) | 3.9 (0.66) | 0.073 |
| Predominant tumor location | |||
| Pancreatic Head | 6 (29) | 14 (47) | |
| Pancreatic Body or Tail | 14 (67) | 12 (40) | 0.013 |
| Diffuse | 1 (5) | 4 (13) | |
| Type of ductal communication | |||
| Main duct or mixed | 4 (22) | 10 (30) | 0.003 |
| Branch duct | 14 (78) | 4 (13) | |
| Size of largest cyst on imaging, mean (range) (cm) | 2.8 (1.6) | 3.5 (1.4) | 0.145 |
| Solid component or mural nodule | |||
| Yes | 3 (14) | 8 (27) | |
| No | 15 (71) | 6 (20) | 0.021 |
Data represent counts (percentages) unless otherwise indicated. Counts may not add up to the total due to missing values, and percentages may not equal 100 due to rounding.
1Benign IPMNs are represented by 6 low-grade and 15 moderate-grade IPMNs.
2Malignant IPMNs are represented by 12 high-grade and 18 invasive IPMNs.