Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 5;7:10523. doi: 10.1038/s41598-017-10868-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Cell viability, ROS level and morphological changes induced by ALC and/or KET in PC12 cells. (a) ALC (60–200 mM) dose-dependently decreased the cell viability of PC12 cells. (b) KET (100–3000 μM) dose-dependently decreased the cell viability of PC12 cells. (c) ALC (60 mM) potentiated KET (100 μM)-induced cell viability decrease in PC12 cells. (d) ALC (60 mM) potentiated KET (100 μM)-induced ROS level increase in PC12 cells by DCFH-DA staining. Scale bar = 20 μm. (e) ALC (60 mM) potentiated KET (100 μM)-induced morphological changes in PC12 cells by transmission electron microscope. Scale bar = 1 μm. The white arrows represent cells with normal nuclei and mitochondria. The red arrows represent abnormal nuclei and mitochondria. *p < 0.05, **p < 0.01 compared with the control group. ^# p < 0.05 compared with the group treated with ALC and KET.