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. 2017 Sep 5;7:10500. doi: 10.1038/s41598-017-10467-y

Table 4.

Association of the functional IFN-λ4-generating polymorphism rs368234815 with atopy in older women in the Polish cohort.

Group Dominant Model (TT/ΔG + ΔG/ΔG) vs TT/TT
OR (crude) 95% CI p OR (adjusted)* 95% CI p
1Women (Asthma) > 50 yr N = 128; atopy, n = 55 0.398 0.188–0.841 0.016 0.402 0.184–0.877 0.021
2Women (Controls) > 50 yr N = 39; atopy, n = 11 0.400 0.098–1.631 0.202 0.366 0.083–1.605 0.171
3Women (Asthma + Controls) > 50 yr N = 167; atopy, n = 66 0.379 0.198–0.724 0.003 0.409 0.208–0.803 0.016

*1, *2 for age; *3 for asthma status and age. A dominant model of inheritance is shown with significant results (p < 0.05) in bold. No significant association under any group/sub/group was seen using the recessive model of inheritance.