Table 5.
Fold-change in mRNA expression of collagen genes at P0 compared to E12.5.
| Gene | Name | Fold Change in Expression P0 vs E12.5 | p value |
|---|---|---|---|
| Col1a1 | Collagen I alpha 1 | 8.65 | 1.20E-07 |
| Col1a2 | Collagen I alpha 2 | 5.54 | 7.67E-09 |
| Col3a1 | Collagen III alpha 1 | −3.87 | 4.94E-05 |
| Col4a1 | Collagen IV alpha 1 | −6.88 | 3.44E-11 |
| Col4a2 | Collagen IV alpha 2 | −5.70 | 1.97E-09 |
| Col4a5 | Collagen IV alpha 5 | −6.18 | 1.63E-16 |
| Col4a6 | Collagen IV alpha 6 | −5.10 | 1.48E-03 |
| Col9a1 | Collagen IX alpha 1 | −7.31 | 4.85E-09 |
| Col9a2 | Collagen IX alpha 2 | −20.46 | 6.12E-26 |
| Col9a3 | Collagen IX alpha 3 | −4.34 | 1.98E-05 |
| Col5a3 | Collagen V alpha 3 | 4.29 | 1.07E-03 |
| Col6a1 | Collagen VI alpha 1 | 7.68 | 8.97E-08 |
| Col6a2 | Collagen VI alpha 2 | 5.80 | 2.15E-05 |
| Col10a1 | Collagen X alpha 1 | 8.88 | 2.41E-12 |
| Col11a1 | Collagen XI alpha 1 | −3.33 | 1.67E-03 |
| Col12a1 | Collagen XII alpha 1 | −2.79 | 3.45E-04 |
| Col14a1 | Collagen XIV alpha 1 | −4.59 | 6.75E-11 |
| Col19a1 | Collagen XIX alpha 1 | −4.94 | 1.79E-05 |
| Col17a1 | Collagen XVII alpha 1 | −3.42 | 3.93E-03 |
| Col18a1 | Collagen XVIII alpha 1 | −5.20 | 8.01E-07 |
| Col20a1 | Collagen XX alpha 1 | −4.20 | 1.12E-04 |
| Col22a1 | Collagen XXII alpha 1 | 4.18 | 2.15E-05 |
| Col23a1 | Collagen XXIII alpha 1 | −4.69 | 8.56E-06 |
| Col25a1 | Collagen XXV alpha 1 | −4.18 | 3.20E-05 |
| Col26a1 | Collagen XXVI alpha 1 | −9.80 | 1.02E-13 |
| Col27a1 | Collagen XXVII alpha 1 | −6.74 | 5.99E-09 |
| Col28a1 | Collagen XXVIII alpha 1 | 5.28 | 1.64E-02 |
N = 4, Differential expression analyzed by DESeq2 and p values adjusted for false discovery rate.