Table 4.
Multivariate logistic regression for effect of insulin resistance on lipoprotein subfraction profile.
| Variables (%) | Raw data | Model A | Model B | |||
|---|---|---|---|---|---|---|
| OR | 95% CI | AOR | 95% CI | AOR | 95% CI | |
| VLDL | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 1.974 | [0.921; 4.230] | 2.205 | [0.965; 5.038] | 2.332 | [1.007; 5.404] |
|
| ||||||
| HDL2 | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 0.283 | [0.141; 0.571] | 0.267 | [0.129; 0.552] | 0.230 | [0.108; 0.493] |
|
| ||||||
| HDL3 | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 0.322 | [0.160; 0.645] | 0.302 | [0.146; 0.625] | 0.298 | [0.142; 0.625] |
|
| ||||||
| HDL5 | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 1.850 | [0.881; 3.884] | 1.843 | [0.873; 3.890] | 1.897 | [0.890; 4.044] |
|
| ||||||
| HDL6 | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 3.367 | [1.460; 7.766] | 3.726 | [1.579; 8.793] | 3.936 | [1.631; 9.498] |
|
| ||||||
| HDL7 | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 1.926 | [0.919; 4.038] | 1.927 | [0.917; 4.047] | 1.980 | [0.930; 4.216] |
|
| ||||||
| HDL8 | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 2.305 | [1.504; 5.039] | 2.305 | [1.042; 5.098] | 2.363 | [1.025; 5.445] |
|
| ||||||
| HDL9 | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 1.631 | [0.772; 3.446] | 1.367 | [0.771; 3.474] | 1.755 | [0.806; 3.822] |
|
| ||||||
| HDL LARGE | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 0.249 | [0.123; 0.505] | 0.232 | [0.111; 0.484] | 0.213 | [0.099; 0.457] |
|
| ||||||
| HDL INTERMETDIATE | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 3.367 | [1.460; 7.766] | 3.843 | [1.606; 9.197] | 4.698 | [1.855; 11.901] |
|
| ||||||
| HDL SMALL | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 2.400 | [1.099; 5.239] | 2.429 | [1.110; 5.319] | 2.486 | [1.115; 5.543] |
|
| ||||||
| LDL SMALL | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 2.826 | [1.263; 6.324] | 2. 794 | [1.237; 6.310] | 3.075 | [1.341; 7.051] |
|
| ||||||
| Phenotype non-A | ||||||
| Non-IR group | 1.000 | 1.000 | 1.000 | |||
| IR group | 3.011 | [1.424; 6.366] | 3.001 | [1.404; 6.416] | 3.176 | [1.469; 6.867] |
n = 181. Model A: adjusted for gender and age. Model B: adjusted for gender, age, smoking, statin, and fibrate. VLDL: very low-density lipoprotein; HDL-C: high-density lipoprotein cholesterol; non-IR group: individuals without insulin resistance; IR group: with insulin resistance.