Table 2.
| Normal | MTX + saline | MTX + lactulose | |
|---|---|---|---|
| Plasma TGF-beta (pg/ml) | 5.8 ± 0.9 | 48.5 ± 4.2∗∗ | 26.1 ± 4.4# |
| Plasma MDA (nM) | 41.09 ± 5.1 | 216.8 ± 12.6∗∗ | 105.9 ± 10.07## |
| Plasma TNF-alpha (pg/ml) | 21.9 ± 3.1 | 88.5 ± 7.2∗∗ | 35.03 ± 6.4# |
| Plasma pentraxin 3 (ng/ml) | 1.17 ± 0.12 | 3.1 ± 0.34∗∗ | 1.5 ± 0.71## |
| ALT (IU/l) | 22.5 ± 3.08 | 74.6 ± 4.4∗∗ | 48.9 ± 7.01# |
| Liver MDA (nmol/g tissue) | 22.4 ± 2.5 | 71.8 ± 6.18∗∗ | 55.21 ± 9.2# |
∗∗ p < 0.0001, MTX + lactulose group compared with normal group. ##p < 0.0001, MTX + lactulose group compared with MTX + saline group. #p < 0.05, MTX + lactulose group compared with MTX + saline group.