Table 2.

Model parameters.

Parameter	Description	Values	Units h = hours, c = cell	Reference
aH	Birth rate of CD4 T	10−4	ch−1	[10]
μ H	Death rate of CD4 T	0.005	h−1	[10]
r H	Max proliferation of CD4 T	1	c−1h−1	[10]
K H	Carrying capacity of CD4 T	1	c	[10]
a C	Birth rate of CD8 T	10−4	c−1h−1	[10]
μ C	Death rate of CD8 T	0.005	h−1	[10]
r C	Max proliferation of CD8 T	4∗10−7	c−1h−1	[10]
K C	Carrying capacity of CD8T	1	c	[10]
r T	Tumor growth rate	0.002	h−1	Ad hoc value
a T	Maximum efficiency of cytotoxic cells	0.1136	h−1	Ad hoc value
τ	DC arriving time delay at lymph nodes	232	h	Ad hoc value
K T	Tumor carrying capacity	1012	c	[6]
μ D	Rate death of DCs	0.009625	h−1	[7]
r I	IL-2 production by CD4 T	10−2	c−1h−1	[10]
μ IC	IL-2 uptake by CD8 T	10−7	c−1h−1	[10]
μ I	IL-2 degradation rate	10−2	h−1	[10]
e T	Michaelis constant	50	c−1	[6]
a Tβ	Michaelis constant	0.69	none	[6]
e Tβ	Michaelis constant	104	pg	[6]
r Tβ	Production rate of TGF-β	5.57 × 10−6	pg(ch)−1	[6]
μ β	Degradation rate of TGF-β	6.93	h−1	[6]
a γC	Release rate per single CTL	1.02∗10−4	pg · c−1 · ml−1 · h−1	[6]
μ γ	Degradation of Fγ	0.102	h−1	[6]
g Ml	Receptor production	1.44	rec · c−1 · h−1	[6]
a Mlγ	Maximal effect of IFN-c	2.89	rec · c−1 · h−1	[6]
e Mlγ	Michaelis parameter	3.38∗105	pg	[6]
μ Ml	Degradation of MI	0.0144	h−1	[6]
e f	Active DC percentage	0.05	c	[8]