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. 2017 Aug 22;2017:1791403. doi: 10.1155/2017/1791403

Figure 4.

Figure 4

Effects of LJF-HE on the mRNA expression levels of cytokines in the joint tissues of rats with MIA-induced OA. (a) Representative histological analysis (H&E staining) of the knee joint in MIA-induced OA. (b–e) The mRNA expression levels of IL-1β, IL-6, COX-2, and TNF-α in the joint tissues of rats with MIA-induced OA were measured by real-time PCR. # indicates p < 0.05 when compared to saline group (NC). ∗ indicates p < 0.05 and ∗∗ indicates p < 0.01 when compared to the control group (CTL).