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. 2017 Jul 28;14(4):2801–2808. doi: 10.3892/etm.2017.4846

Figure 5.

Figure 5.

ALDH/PI CSCs exhibit higher tumorigenicity than ALDH CSCs in vitro and in vivo. (A) ALDH CSCs formed a significantly lower number of colonies than the ALDH/PI CSCs as assessed by a colony formation assay. (B) Mice transplanted with ALDH/PI CSCs formed tumors earlier and formed significantly larger tumors than mice transplanted with ALDH CSCs. All data are presented as the mean ± standard deviation of three independent experiments. *P<0.05 vs. ALDH. ALDH, aldehyde dehydrogenase; CSCs, cancer stem cells; PI, propidium iodide.