Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 28;14(4):2853–2862. doi: 10.3892/etm.2017.4847

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Ma et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 2. — (A) Levels of IGF-1R mRNA in each group were detected by reverse transcription-quantitative polymerase chain reaction. IGF-1R expression was inhibited by transfection with siRNA-1, siRNA-2 and siRNA-3. Expression of IGF-1R mRNA in the three siRNA groups was significantly lower than that of the blank control group Data are expressed as the mean + standard deviation. *P<0.05, **P<0.01 vs. the blank control group. (B) The siRNA silencing efficiency. siRNA silencing efficiency=(1-IGF-1R expression in the siRNA group/IGF-1R expression in the blank group) ×100%. siRNA-2 exhibited the highest efficiency (72%) of silencing. **P<0.01 vs. the positive and negative groups. siRNA, small interfering RNA; IGF-1R, insulin-like growth factor receptor 1.