Table 2.
Pairwise correlation and simple linear regression results between fNIRS parameters, and MMSE score.
| Left PFC | Right PFC | |||
|---|---|---|---|---|
| m | R | m | R | |
| NUMBER OF ACTIVATED MEASUREMENT CHANNELS, | ||||
| Nleft PFC/right PFC vs. MMSE SCORE | ||||
| HC | 0.1919 | 0.0540 | 0.3868 | 0.1393 |
| MCI | −0.1154 | −0.0634 | 0.1731 | 0.1032 |
| Mild AD | 0.2517 | 0.2914 | 0.0412 | 0.0429 |
| oxy-Hb CONCENTRATION CHANGE DURING THE ACTIVATION PERIOD, | ||||
| Δoxy−Hbleft PFC/right PFC vs. MMSE SCORE | ||||
| HC | 0.0010 | 0.0478 | 0.0035 | 0.1467 |
| MCI | 0.0152 | 0.5886 | 0.0086 | 0.4144 |
| Mild AD | −0.0006 | −0.0732 | −0.0019 | −0.2258 |
| TIME TAKEN TO ACHIEVE 25% OF PEAK ACTIVATION LEVEL, | ||||
| tleft PFC/right PFC vs. MMSE Score | ||||
| HC | −0.8478 | −0.3394 | −0.8567 | −0.3713 |
| MCI | −0.4644 | −0.3340 | 0.4153 | 0.3143 |
| Mild AD | 0.0961 | 0.0729 | −0.3606 | −0.2733 |
| SLOPE IN THE FIRST 5 S AFTER TASK ONSET, | ||||
| mleft PFC/right PFC vs. MMSE SCORE | ||||
| HC | 0.0008 | 0.2040 | 0.0020 | 0.2926 |
| MCI | 0.0007 | 0.2028 | −0.0001 | −0.0394 |
| Mild AD | 0.0000 | −0.0026 | 0.0004 | 0.2663 |
m, slope of the linear regression; R, correlation coefficient between the two parameters; HC, healthy control; MCI, mild cognitive impairment; mild AD, mild Alzheimer's disease.