Figure 5.

Effects of paeonol on the apoptosis pathway components HIF-1α and VEGF in the ovarian cancer cell lines SKOV-3 and OVCAR-3, as observed by (A) reverse transcription-polymerase chain reaction and (B) western blotting. L1, control; L2, 50 µM paeonol only; L3, 100 µM paeonol only; L4, 2 Gy radiation only; L5, 4 Gy radiation only; L6, 6 Gy radiation only; L7, 50 µM paeonol + 2 Gy radiation; L8, 100 µM paeonol + 2 Gy radiation; L9, 50 µM paeonol + 4 Gy radiation; L10, 100 µM paeonol + 4 Gy radiation; L11, 50 µM paeonol + 6 Gy radiation; L12, 100 µM paeonol + 6 Gy radiation. HIF, hypoxia inducible factor; VEGF, vascular endothelial growth factor.