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Table 2.

Cargoes undergoing transcytosis in polarized epithelia

Cargo References
Immunoglubulins
IgA/pIgR Apodaca et al. 1994; Mostov 1994; Verges et al. 2004; Moon et al. 2014
IgG/ FcRn Claypool et al. 2002; Li et al. 2011
IgE Palaniyandi et al. 2015
EGF Kozu et al. 1997; Maratos-Flier et al. 1987; Brandli et al. 1991
Endogenous cargoes
Transferrin Fishman et al. 1987; Roberts et al. 1993; Skarlatos et al. 1995; Broadwell et al. 1996; Descamps et al. 1996; Burdo et al. 2003; Du et al. 2013; Manich et al. 2013; Wiley et al. 2013;
Insulin Azizi et al. 2015
DARC Lee et al. 2003; Pruenster et al. 2009; Novitzky-Basso and Rot 2012; Minten et al. 2014
SorLA Klinger et al. 2016
LDL Candela et al. 2008; Bian et al. 2014; Li et al. 2014; Zhang et al. 2014
PI-CALM Zhao et al. 2015
A1AT Lockett et al. 2014
HTLV-1 Martin-Latil et al. 2012
Viral and bacterial pathogens
P97 Tang et al. 2007
Botulinum toxin Maksymowych and Simpson 1998; Ahsan et al. 2005; Miyashita et al. 2014
Listeria monocytegenes Nikitas et al. 2011
Epstein–Barr virus Tugizov et al. 2013
HIV Dohgu et al. 2011; Gupta et al. 2013; Kinlock et al. 2014
Cholera toxin Lencer et al. 1995; Saslowsky et al. 2013
Shiga toxin Malyukova et al. 2008, 2009; Lukyanenko et al. 2011