Table V.
Effect of dietary level of vitamin B6 on expression of genes related to myogenesis and sarcopenia in gastrocnemius muscle of rats.
| Relative gene expression | |||
|---|---|---|---|
| Gene | 1 mg/kg PN HCl | 7 mg/kg PN HCl | 35 mg/kg PN HCl |
| Myogenin | 1.00±0.06 | 1.52±0.20a | 0.82±0.05b |
| MuRF1 | 1.00±0.07 | 1.35±0.17 | 1.21±0.16 |
| Myf-6 | 1.00±0.09 | 1.33±0.32 | 1.06±0.33 |
| MyoD1 | 1.00±0.12 | 1.27±0.18 | 1.09±0.19 |
| Myf-5 | 1.00±0.01 | 1.24±0.11 | 1.06±0.06 |
| Atrogin-1 | 1.00±0.15 | 1.24±0.18 | 1.46±0.10 |
| RPB3 | 1.00±0.06 | 1.08±0.03 | 0.95±0.02 |
| Sp1 | 1.00±0.10 | 1.08±0.06 | 0.93±0.07 |
Values are presented as the mean ± standard error of the mean. n=6 or 8.
a
P<0.05 vs. 1 mg/kg group.
b
Indicates studies using 6 animals and others are the data of 8 animals. PN, pyridoxine; MuRF1, muscle ring-finger protein-1; Myf, myogenic factor; MyoD1, myogenic differentiation 1; RPB3, RNA polymerase B3; Sp1, specificity protein.