Table 3. Adipokines and glycemic parameters before and after intervention .
Parameter | Probiotic (n=30) | P * | Prebiotic (n=29) | P * | Placebo (n=30) | P * | P ** | |
Leptin (ng/mL) |
Before | 73.10±26.78 | < 0.001 | 80.34±29.71 | < 0.001 | 75.85±26.96 | 0.629 | 0.000† |
After | 48.6±13.56 | 56.86±22.83 | 74.41±26.17 | |||||
Adiponectin (µg/mL) | Before | 24.36±11.11 | < 0.001 | 27.82±10.43 | < 0.001 | 25.78±9.45 | 0.005 | 0.837 |
After | 40.73±24.14 | 43.9±15.66 | 39.37±24.17 | |||||
FBS | Before | 91.47±9.86 | 0.349 | 95.31±17.67 | 0.026 | 98.3±24.16 | 0.368 | 0.296 |
After | 88.83±10.14 | 89.41±16.76 | 96.23±20.62 | |||||
Insulin (µ IU/mL) |
Before | 16.7±8.72 | 0.004 | 15.06±6.26 | < 0.001 | 17.44±11.66 | 0.382 | 0.004† |
After | 12.92±9.32 | 11.42±4.50 | 18.49±12.76 | |||||
HOMA-IR | Before | 3.82±2.14 | 0.01 | 3.62±1.89 | < 0.001 | 4.7±5.87 | 0.959 | 0.026† |
After | 2.96±2.53 | 2.58±1.35 | 4.8±5.45 | |||||
QUICKI | Before | 0.32±0.024 | 0.001 | 0.32±0.021 | < 0.001 | 0.31±0.024 | 0.614 | 0.000† |
After | 0.33±0.031 | 0.34±0.023 | 0.31±0.022 |
Values are reported as mean±SD.
P*: Obtained from the paired samples t test for comparison of data between the beginning and end of the study.
P**: Obtained from ANCOVA test adjusted for the baseline values among the intervention and placebo groups.
†: Significant difference between probiotic and prebiotic groups with placebo group that obtained from Bonferoni post hoc