Table 1.
Cohort characteristics
n | 63 |
FTLD Type (A, B, C, E) | 17, 21, 20, 5 |
Age onset | 62.1 (9.2) |
Age Death | 68.8 (10.2) |
Sex (m, f) | 32, 31 |
Brain Wt | 1110.0 g (188.6) |
GRN Cases | 12 |
C9orf72 Cases | 17 |
Clinical Diagnosis | |
AD | 8 |
ALS | 3 |
CBD | 3 |
FTD-bvFTD | 22 |
FTD-NOS | 14 |
FTD-PPA | 12 |
MID | 1 |
PSP | 1 |
Primary Neuropath Diagnosis | FTLD-TDP |
Secondary Neuropath Diagnosis | |
AD | 9 |
AGD | 5 |
ALS | 1 |
HS | 2 |
LBD | 1 |
None | 21 |
PART | 24 |
All data are expressed as mean (standard deviation). Clinical diagnoses reflect a patient’s diagnosis at time of death. AD alzheimer’s disease, AGD argyrophilic grain disease, ALS amyotrophic lateral sclerosis, CBD corticobasal syndrome, FTD-bvFTD behavioral variant FTD; FTD-NOS FTD not otherwise specified, FTD-PPA primary progressive aphasia, HS hippocampal sclerosis, LBD lewy body dementia, MID multi-infarct dementia, PART primary age-related tauopathy, PSP progressive supranuclear palsy