Scheme 3. Synthesis of Compound 11a.
a Reagents: (a) NaBH4, BF3·(OEt)2, THF; (b) BCl3, TBAI, CH2Cl2; (c) MsCl, pyridine; (d) Pd/C, EtOH, HCl, H2; (e) trans-2-methylcinnamaldehyde, NaBH(OAc)3, 1,2-dichloroethane; (f) NaOH, CH3OH.
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