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. Author manuscript; available in PMC: 2017 Sep 6.
Published in final edited form as: Bioorg Med Chem Lett. 2015 Mar 14;25(9):1971–1975. doi: 10.1016/j.bmcl.2015.03.016

Figure 2.

Figure 2

Aqueous solubility and in vitro anti-cancer activities of compounds in Library 1 (R3 = H). Aqueous solubility of compounds (A) was determined using a method described in Supporting information. Cytotoxicity of compounds in normal human fibroblast (NHFB) (B), H460 (C) and H460TaxR (D) were measured using SRB method with a compound concentration of 10 µM. Cell viability in DMSO was designated as 100%.