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. Author manuscript; available in PMC: 2017 Sep 6.
Published in final edited form as: Bioorg Med Chem Lett. 2015 Mar 14;25(9):1971–1975. doi: 10.1016/j.bmcl.2015.03.016

Figure 5.

Figure 5

Anti-cancer pharmacophore generated using the 10 active molecules. The graph shows the four most active (2, 4, 12, 33) compounds aligned. Green dots represent hydrophobic features; blue regions represent hydrogen bond acceptors.