(A) Hematocrit values at baseline and after PSA in males (M), females (F), sham-operated and OVX mice. (B) Wet/dry lung weight ratios of male and female mice 2 h after anaphylaxis. In A–B, n=6/group. (C) Representative H&E stained lung slides from a male and female mouse 2 h after IgE/Ag-induced PSA showing peri-bronchial edema (arrows) and red blood cells accumulated in airspace (arrowheads). Scale bar: 100μm. *P<0.05, **P<0.01, *** P<0.001.