Table 2.
Estimates of excess relative risk per Sv (95% confidence interval) for all cancers excluding leukaemia, solid cancers, and leukaemia excluding chronic lymphocytic leukaemia, for nuclear workers and survivors of A bomb in Japan *
|
15 country study
|
Atomic bomb survivors (men exposed at age 20-60)
|
|||
|---|---|---|---|---|
| No of cancers | Risk | No of cancers | Risk† | |
| All cancers excluding leukaemia | 5024 | 0.97 (0.14 to 1.97) | ||
| Solid cancers | 4770 | 0.87 (0.03 to 1.88) | 3246 | 0.32 ‡ (0.01 to 0.50) |
| Leukaemia excluding CLL: | ||||
| Linear model | 196 | 1.93 (<0 § to 8.47) | 83 | 3.15 ¶ (1.58 to 5.67) |
| Linear quadratic model | 1.54 ** (−1.14 to 5.33) | |||
CLL=chronic lymphocytic leukaemia.
Colon dose used for all cancers and solid cancer analyses, bone marrow dose for leukaemia.
Note that because analyses were restricted to men aged 20-60 at exposure the confidence intervals are much wider than those presented by other investigators13,14 and are based on the full cohort.
Analyses carried out at IARC with excess relative risk model that allows for age at exposure modification, adjusted for attained age, calendar period, and city. Estimate for men exposed at age 35.
Estimate on boundary of parameter space.
Analyses carried out at IARC with constant excess relative risk model, adjusted for attained age, calendar period, and city.
Analyses carried out at IARC—linear term of linear quadratic model—preferred model for describing leukaemia mortality in analyses of data on A bomb survivors.14