Table 2.
Overexpressed (Positive J5) and Underexpressed (Negative J5) Genes in the Ipsilateral Hippocampus 24 H after Blast Exposure
| Rank | Name | J5 | Accession_no. |
|---|---|---|---|
| 1 | 68224_PRED_glial_fibrillary_acidic_protein_(Gfap) | 238.816 | XM_579387.1 |
| 2 | 64138_synaptic_vesicle_glycoprotein_2b_(Sv2b) | −178.53 | NM_057207.2 |
| 3 | 66032_PRED_similar_to_glyceraldehyde-3-phosphate_dehydrogenase_(LOC500506) | 104.238 | XM_575868.1 |
| 4 | 65073_PRED_transferrin_(Tf) | −93.134 | XM_579389.1 |
| 5 | 59800_PRED_similar_to_ORF4_(LOC361942) | −76.364 | XM_342241.2 |
| 6 | 53757_PRED_similar_to_Tubulin_alpha-2_chain_(alpha-tubulin_2)_(LOC500929) | −74.248 | XM_576339.1 |
| 7 | 64101_PRED_hypothetical_gene_supported_by_BC087105_(LOC500856) | −72.23 | XM_580130.1 |
| 8 | 66108_PRED_3-hydroxy-3-methylglutaryl-coenzyme_A_synthase_1_(Hmgcs1) | −70.16 | XM_579405.1 |
| 9 | 70349_heat_shock_27kDa_protein_1_(Hspb1) | 69.913 | NM_031970.1 |
| 10 | 53820_PRED_similar_to_Rpl17_protein_(LOC361869) | 67.616 | XM_342164.2 |
| 11 | 67056_PRED_similar_to_testin_(LOC503278) | 66.574 | XM_578812.1 |
| 12 | 56963_PRED_similar_to_ORF4_(LOC498048) | −65.987 | XM_573248.1 |
| 13 | 60315_diazepam_binding_inhibitor_(Dbi) | −65.766 | NM_031853.3 |
| 14 | 58313_PRED_similar_to_glyceraldehyde-3-phosphate_dehydrogenase_(LOC500983) | 64.087 | XM_576394.1 |
| 15 | 67501_PRED_ectonucleotide_pyrophosphatase/phosphodiesterase_2_(Enpp2) | −63.742 | XM_579590.1 |
| 16 | 68346_tubulin_alpha_1_(Tuba1) | −63.423 | NM_022298.1 |
| 17 | 56273_BCL2/adenovirus_E1B_19_kDa-interacting_protein_3_(Bnip3) | −63.352 | NM_053420.2 |
| 18 | 53205_PRED_similar_to_60S_ribosomal_protein_L17_(L23)_(amino_acid_starvation-induced_protein)_(ASI)_(LOC367398) | −61.607 | XM_576661.1 |
| 19 | 65816_guanine_deaminase_(Gda) | 61.181 | NM_031776.1 |
| 20 | 66022_PRED_plakophilin_4_(pred)_(Pkp4_pred) | −60.531 | XM_215733.3 |
| 21 | 50398_PRED_similar_to_RIKEN_cDNA_2410116I05_(LOC363377) | −59.531 | XM_343712.2 |
| 22 | 60643_serum/glucocorticoid_regulated_kinase_(Sgk) | 57.752 | NM_019232.1 |
| 23 | 65851_PRED_similar_to_LRRG00116_(LOC362543) | −57.401 | XM_342864.2 |
| 24 | 64861_cyclic_nucleotide_phosphodiesterase_1_(Cnp1) | −56.878 | NM_012809.1 |
| 25 | 66358_actin_beta_(Actb) | 55.115 | NM_031144.2 |
| 26 | 64690_growth_associated_protein_43_(Gap43) | 55.06 | NM_017195.1 |
| 27 | 64865_ribosomal_protein_L17_(Rpl17) | −54.338 | NM_201415.1 |
| 28 | 64748_N-myc_downstream_regulated_gene_2_(Ndrg2) | −53.958 | NM_133583.1 |
| 29 | 57328_PRED_similar_to_Ac1262_(LOC363492) | −53.4 | XM_343815.2 |
| 30 | 67903_carbonic_anhydrase_2_(Ca2) | −53.371 | NM_019291.1 |
| 31 | 57073_proteolipid_protein_(Plp) | −50.942 | NM_030990.1 |
| 32 | 64064_protease_serine_11_(Igf_binding)_(Prss11) | 49.761 | NM_031721.1 |
| 33 | 53575_metallothionein_(Mt1a) | 48.76 | NM_138826.2 |
| 34 | 66191_ribonuclease_RNase_A_family_4_(Rnase4) | −47.407 | NM_020082.2 |
| 35 | 65814_myelin_and_lymphocyte_protein_(Mal) | −47.3 | NM_012798.1 |
| 36 | 60399_selenoprotein_W_muscle_1_(Sepw1) | −46.179 | NM_013027.1 |
| 37 | 53801_ATPase_H+_transporting_V0_subunit_C_(Atp6v0c) | −46.147 | NM_130823.2 |
| 38 | 57715_PRED_similar_to_LRRG00135_(LOC501637) | −45.936 | XM_577034.1 |
| 39 | 51075_PRED_nel-like_2_homolog_(chicken)_(Nell2) | 45.847 | XM_579504.1 |
| 40 | 58188_glycoprotein_38_(Gp38) | 45.463 | NM_019358.1 |
| 41 | 51219_metallothionein_3_(Mt3) | −44.751 | NM_053968.2 |
| 42 | 56089_N-ethylmaleimide_sensitive_fusion_protein_(Nsf) | 44.528 | NM_021748.1 |
| 43 | 70319_PRED_Jun_D_proto-oncogene_(Jund) | −44.094 | XM_579658.1 |
| 44 | 69046_myelin_oligodendrocyte_glycoprotein_(Mog) | −43.883 | NM_022668.1 |
| 45 | 50141_calcium/calmodulin-dependent_protein_kinase_II_inhibitor_1_(Camk2n1) | −43.749 | NM_173337.1 |
| 46 | 63461_PRED_similar_to_60S_ribosomal_protein_L37a_(LOC500547) | −43.535 | XM_575909.1 |
| 47 | 67911_calreticulin_(Calr) | −42.917 | NM_022399.1 |
| 48 | 52581_protein_phosphatase_3_catalytic_subunit_alpha_isoform_(Ppp3ca) | −42.451 | NM_017041.1 |
| 49 | 64945_reticulon_4_(Rtn4) | −42.348 | NM_031831.1 |
| 50 | 60797_PRED_similar_to_Ac1147_(LOC310926) | 41.71 | XM_227769.2 |
| 51 | 61449_PRED_similar_to_glyceraldehyde-3-phosphate_dehydrogenase_(GAPDH)_(LOC290634) | 41.416 | XM_214287.3 |
| 52 | 65242_PRED_calmodulin_1_(Calm1) | −41.244 | XM_579543.1 |
| 53 | 57628_ARP2_actin-related_protein_2_homolog_(yeast)_(Actr2) | −40.818 | NM_001009268.1 |
| 54 | 55545_tyrosine_3-monooxygenase/tryptophan_5-monooxygenase_activation_protein_zeta_polypeptide_(Ywhaz) | 40.56 | NM_013011.1 |
| 55 | 55306_PRED_similar_to_RIKEN_cDNA_2610042L04_(LOC498371) | 39.677 | XM_573606.1 |
| 56 | 52278_PRED_prion_protein_(Prnp) | 38.656 | XM_579340.1 |
| 57 | 54246_ATPase_Na+/K+_transporting_alpha_2_polypeptide_(Atp1a2) | −38.12 | NM_012505.1 |
| 58 | 47800_fatty_acid_binding_protein_7_brain_(Fabp7) | −38.103 | NM_030832.1 |
| 59 | 62559_tissue_inhibitor_of_metalloproteinase_1_(Timp1) | 37.855 | NM_053819.1 |
| 60 | 56078_tumor_protein_translationally controlled_1_(Tpt1) | −37.607 | NM_053867.1 |
| 61 | 50209_PRED_actin_related_protein_2/3_complex_subunit_5_(pred)_(Arpc5_pred) | 37.341 | XM_341131.2 |
| 62 | 48559_PRED_ribosomal_protein_L37a_(pred)_(Rpl37a_pred) | −37.317 | XM_343587.1 |
| 63 | 65995_ATPase_H+_transporting_V1_subunit_B_isoform_2_(Atp6v1b2) | 37.104 | NM_057213.2 |
| 64 | 54015_PRED_similar_to_L-lactate_dehydrogenase_A_chain_(LDH-A)_(LDH_muscle_subunit)_(LDH-M)_(LOC500965) | 37.018 | XM_576374.1 |
| 65 | 52257_stearoyl-Coenzyme_A_desaturase_2_(Scd2) | −36.929 | NM_031841.1 |
| 66 | 67309_PRED_similar_to_retrovirus-related_POL_polyprotein_(LOC362315) | −36.921 | XM_342631.2 |
| 67 | 66374_LIM_domain_only_4_(Lmo4) | −36.828 | NM_001009708.1 |
| 68 | 58863_PRED_similar_to_Tescalcin_(LOC288689) | 35.721 | XM_213790.3 |
| 69 | 47777_PRED_similar_to_LRRG00135_(LOC501548) | −34.265 | XM_576950.1 |
| 70 | 64580_protein_phosphatase_3_regulatory_subunit_B_alpha_isoform_(calcineurin_B_type_I)_(Ppp3r1) | −33.858 | NM_017309.2 |
| 71 | 67723_tubulin_beta_2_(Tubb2) | −33.638 | NM_199094.1 |
| 72 | 54363_PRED_LOC500721_(LOC500721) | −33.432 | XM_580114.1 |
| 73 | 57098_lysosomal-associated_protein_transmembrane_4A_(Laptm4a) | −33.427 | NM_199384.1 |
| 74 | 48846_myelin_basic_protein_(Mbp) | −33.262 | NM_017026.1 |
| 75 | 48072_phosphatidylethanolamine_binding_protein_(Pbp) | 33.202 | NM_017236.1 |
| 76 | 63688_ubiquinol_cytochrome_c_reductase_core_protein_2_(Uqcrc2) | 33.148 | NM_001006970.1 |
| 77 | 55248_ribosomal_protein_L30_(Rpl30) | 32.804 | NM_022699.2 |
| 78 | 60306_chondroitin_sulfate_proteoglycan_5_(Cspg5)_transcript_variant_1 | −32.792 | NM_019284.1 |
| 79 | 61448_complement_component_1_q_subcomponent_beta_polypeptide_(C1qb) | 32.534 | NM_019262.1 |
| 80 | 55787_PRED_similar_to_RIKEN_cDNA_4930555G01_(LOC498375) | 32.514 | XM_573610.1 |
| 81 | 68428_fasciculation_and_elongation_protein_zeta_1_(zygin_I)_(Fez1) | −32.454 | NM_031066.1 |
| 82 | 61404_cystatin_C_(Cst3) | −32.403 | NM_012837.1 |
| 83 | 59957_calcium/calmodulin-dependent_protein_kinase_II_beta_subunit_(Camk2b) | −32.239 | NM_021739.1 |
| 84 | 55606_malate_dehydrogenase_1_NAD_(soluble)_(Mdh1) | 32.113 | NM_033235.1 |
| 85 | 54601_neurogranin_(Nrgn) | −32.094 | NM_024140.2 |
| 86 | 50017_PRED_similar_to_small_membrane_protein_1_(pred)_(LOC298552) | −31.812 | XM_216545.3 |
| 87 | 53344_ATP_synthase_H+_transporting_mitochondrial_F1_complex_alpha_subunit_isoform_1_(Atp5a1) | 31.591 | NM_023093.1 |
| 88 | 69434_similar_to_Nur77_downstream_protein_2_(MGC105647) | −31.347 | NM_001007008.1 |
| 89 | 61545_chemokine_(C-X3-C_motif)_ligand_1_(Cx3cl1) | −31.229 | NM_134455.1 |
| 90 | 59239_PRED_similar_to_T-complex_associated-testis-expressed_1-like_(Protein_91/23)_(LOC501521) | −31.201 | XM_576923.1 |
| 91 | 64944_nucleophosmin_1_(Npm1) | 30.119 | NM_012992.2 |
| 92 | 66984_PRED_similar_to_glyceraldehyde-3-phosphate_dehydrogenase_(LOC498099) | 29.995 | XM_573304.1 |
| 93 | 62489_PRED_histone_deacetylase_11_(pred)_(Hdac11_pred) | −29.814 | XM_238362.3 |
| 94 | 53421_aldolase_C_fructose-biphosphate_(Aldoc) | −29.776 | NM_012497.1 |
| 95 | 67589_PRED_similar_to_LRRG00116_(LOC500867) | −29.478 | XM_576265.1 |
| 96 | 52641_PRED_similar_to_Eph_receptor_A4_(LOC316539) | −29.462 | XM_244186.3 |
| 97 | 55111_PRED_polyubiquitin_(Ubb) | −28.934 | XM_579661.1 |
| 98 | 54242_vimentin_(Vim) | 28.92 | NM_031140.1 |
| 99 | 60033_tetraspan_2_(Tspan2) | −28.641 | NM_022589.1 |
| 100 | 52135_PRED_nucleoside_phosphorylase_(Np) | −28.542 | XM_214155.3 |
| 101 | 63348_ATPase_Ca++_transporting_cardiac_muscle_slow_twitch_2_(Atp2a2) | −28.174 | NM_017290.1 |
| 102 | 50549_PRED_similar_to_ribosomal_protein_L15_(LOC498143) | 28.158 | XM_573353.1 |
| 103 | 57629_SNRPN_upstream_reading_frame_(Snurf) | 28.101 | NM_130738.1 |
| 104 | 53861_PRED_cyclin_I_(pred)_(Ccni_pred) | −28.1 | XM_214007.3 |
| 105 | 54685_asparaginase-like_sperm_autoantigen_(Asrgl1) | −28.073 | NM_145089.2 |
| 106 | 57519_annexin_A3_(Anxa3) | 27.934 | NM_012823.1 |
| 107 | 55334_ribosomal_protein_L9_(Rpl9) | −27.874 | NM_001007598.2 |
| 108 | 63257_cystatin_B_(Cstb) | 27.841 | NM_012838.1 |
| 109 | 63580_lysosomal_membrane_glycoprotein_1_(Lamp1) | −27.467 | NM_012857.1 |
| 110 | 56027_heat_shock_70kD_protein_5_(Hspa5) | −27.204 | NM_013083.1 |
| 111 | 56464_Sec11-like_3_(S_cerevisiae)_(Sec11l3) | −27.158 | NM_153628.1 |
| 112 | 48685_solute_carrier_family_25_(mitochondrial_carrier;_adenine_nucleotide_translocator)_member_5_(Slc25a5) | 26.761 | NM_057102.1 |
| 113 | 66571_clusterin_(Clu) | 26.725 | NM_053021.2 |
| 114 | 50412_beta-2_microglobulin_(B2m) | 26.336 | NM_012512.1 |
| 115 | 59171_mitogen_activated_protein_kinase_kinase_1_(Map2k1) | 26.192 | NM_031643.3 |
| 116 | 48424_putative_ISG12(a)_protein_(isg12(a)) | −26.13 | NM_203410.1 |
| 117 | 61561_ferritin_heavy_polypeptide_1_(Fth1) | −26.123 | NM_012848.1 |
| 118 | 60484_serine_protease_inhibitor_(Spin2c) | 25.975 | NM_031531.1 |
| 119 | 52089_PRED_similar_to_ribosomal_protein_L21_(LOC293642) | −25.798 | XM_212883.3 |
| 120 | 60218_dynein_cytoplasmic_intermediate_chain_1_(Dncic1) | 25.396 | NM_019234.1 |
| 121 | 52149_PRED_similar_to_solute_carrier_family_25_member_5_(LOC498885) | 25.28 | XM_574173.1 |
| 122 | 60826_PRED_similar_to_glycolipid_transfer_protein_(LOC288707) | −25.017 | XM_213793.3 |
| 123 | 54968_crystallin_alpha_B_(Cryab) | 24.924 | NM_012935.2 |
| 124 | 58278_calmodulin_2_(Calm2) | −24.813 | NM_017326.1 |
| 125 | 48422_Ras-related_GTP-binding_protein_ragA_(Rraga) | 24.729 | NM_053973.1 |
| 126 | 62993_peroxiredoxin_6_(Prdx6) | −24.669 | NM_053576.1 |
| 127 | 66828_pregnancy_upregulated_nonubiquitously_expressed_CaM_kinase_(Pnck) | 24.604 | NM_017275.1 |
| 128 | 69562_dynamin_1_(Dnm1) | 24.573 | NM_080689.2 |
| 129 | 59917_PRED_cytochrome_c_oxidase_subunit_vIa_polypeptide_1_(Cox6a1) | −24.313 | XM_341094.2 |
| 130 | 69749_solute_carrier_family_3_(activators_of_dibasic_and_neutral_amino_acid_transport)_member_2_(Slc3a2) | 24.305 | NM_019283.1 |
| 131 | 65297_neurofilament_light_polypeptide_(Nfl) | 23.585 | NM_031783.1 |
| 132 | 51621_PRED_similar_to_glyceraldehyde-3-phosphate_dehydrogenase_(GAPDH)_(LOC295452) | 23.542 | XM_227696.3 |
| 133 | 69972_SPARC-like_1_(mast9_hevin)_(Sparcl1) | −23.518 | NM_012946.1 |
| 134 | 69307_melanoma_antigen_family_D_1_(Maged1) | 23.505 | NM_053409.1 |
| 135 | 53094_G_protein-coupled_receptor_56_(Gpr56) | −23.49 | NM_152242.1 |
| 136 | 67819_aldolase_A_(Aldoa) | 23.179 | NM_012495.1 |
| 137 | 52165_integral_membrane_protein_2B_(Itm2b) | 22.974 | NM_001006963.1 |
| 138 | 53919_PRED_similar_to_cDNA_sequence_AY358078_(LOC501245) | 22.889 | XM_576664.1 |
| 139 | 49011_macrophage_migration_inhibitory_factor_(Mif) | −22.813 | NM_031051.1 |
| 140 | 63888_glucose_phosphate_isomerase_(Gpi) | 22.548 | NM_207592.1 |
| 141 | 68784_thyrotropin_releasing_hormone_(Trh) | 22.292 | NM_013046.2 |
| 142 | 48590_ribosomal_protein_S10_(Rps10) | −22.227 | NM_031109.1 |
Results are shown in order of decreasing J5 score.