Table 1.
Clinical information and cell counts
| Asthma | Controls | ||
|---|---|---|---|
| Mild | Moderate/severe | ||
| Gender (female:male) | 22:15 | 6:27 | 11:19 |
| Age (years) | 28 (21–57) | 55 (29–73) | 26 (19–69) |
| FEV1 (percent predicted)* | 100 (81.6–133.0) | 58.7 (31.5–69.76)‡ | 106.4 (80.0–131.2) |
| Total cell number (×106/ml) | 1.8 (0.9–5.8) | 2.3 (2.1–2.3) | 1.6 (0.8–3.1) |
| Neutrophils* (×106/ml) | 0.072 (0.0015–0.16) | 0.0667‡ (0.017–0.135) | 0.0147 (0.00–0.069) |
| Eosinophils* (×106/ml) | 0.0589† (0.0–0.112) | 0.0637† (0.0247–0.165) | 0.00 (0.00–0.20) |
| Lymphocytes (×106/ml) | 0.09 (0.03–1.11) | 0.0923 (0.0305–0.254) | 0.10 (0.0288–0.495) |
| Macrophage (×106/ml) | 1.606 (0.797–5.46) | 2.072 (0.757–3.029) | 1.438 (0.74–2.83) |
Data are expressed as the median (range). *Kruskal–Wallis test P<0.05 between asthma and control; †P<0.0001 versus controls; ‡Mann–Whitney U-test and P<0.0001 (vs. mild and controls). FEV1: Forced expiratory volume in 1 s.