Skip to main content
. 2017 Sep 1;8:660. doi: 10.3389/fphys.2017.00660

Figure 4.

Figure 4

The stimulatory effect of CCK on Bodipy-FA uptake is inhibited by phloretin or SSO. (A) Cellular Bodipy-FA uptake was significantly increased when incubated with 10 pM CCK. This increase was abolished in the presence of 200 μM phloretin. Phloretin alone caused a significant decrease in Bodipy-FA uptake to below the control level. (B) The stimulatory effect of CCK was also completely inhibited in the presence of 1 μM SSO. SSO alone had no effect on mean cell fluorescence compared with control. Cells were preincubated for 15 min with either inhibitors, before application of Bodipy-FA for 2 min. Means represent replicates performed in triplicate and error bars represent SEM (n = 3) *p > 0.05, **p > 0.01 compared to control; ++p > 0.01 compared to CCK.